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The University of Southampton

CHEM6120 Advanced Chemistry for Euromasters Students

Module Overview

Aims and Objectives

Module Aims

The Basis of Fundamental knowledge behind the rational analysis of organic synthesis. The Basic and advanced knowledge of asymmetric chemistry and synthesis.

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Understanding the process of “breaking down” a target molecule into available starting materials by means of imaginary breaking bonds (disconnections) and by the conversion of one functional group to another by efficient chemical reactions (functional group interconversions), taking into accounts chemo-, regio-, stereoselectivity aspects of these reactions.
  • Understanding the basis of asymmetry in chemistry including the definitions, the analytical methods used for the determination of the asymmetry and the presentation of the various methodologies to prepare enantiopur molecules


• History, introduction, the basic concepts of retrosynthetic analysis • Latent polarity, disconnection of mono- or bifunctional compounds, functional group interconversion, • Strategy and planning of the synthesis • Chemoselectivity and protecting groups • Regio- and stereoselectivity • Basic elements of asymmetry in chemistry • Analytical methods in asymmetric synthesis • Main methodologies for the asymmetric synthesis: • Using enantiopure substrate • Using a chiral auxiliary • Using a chiral reagent • Using a chiral catalyst • Applications to the synthesis of natural products

Learning and Teaching

Teaching and learning methods

Lectures and workshops.

Independent Study130
Practical classes and workshops4
Total study time150



MethodPercentage contribution
Examination 100%


MethodPercentage contribution
Examination 100%
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