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HPRS1023 Scientific Basis of Cardiovascular/Respiratory and Sleep Science Part 1

Module Overview

The overall aim of this module is to ensure the student understands the breadth of the application of the science across the cardiovascular science / respiratory & sleep science and is able to work safely within these environments.

Aims and Objectives

Module Aims

See the learning outcomes listed below.

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Outline the anatomy, physiology and pathophysiology relating to cardiac and vascular science.
  • Outline the anatomy, physiology and pathophysiology relating to respiratory and sleep science.
  • Become the recipients of research evidence in healthcare science by considering the range of research activity in healthcare science cardiac physiology, respiratory and sleep science by accessing peer reviewed journals and associated literature
Subject Specific Intellectual and Research Skills

Having successfully completed this module you will be able to:

  • Use correct terminology when discussing scientific issues


Indicative Content Anatomy, physiology and pathophysiology applied to cardiology, respiration and sleep. • Cardiac and vascular system • Respiratory system • Sleep / wake cycle and common sleep disorders • Pathophysiology of key body systems related to physiological sciences • Introduction to cardiology and vascular science • Anatomy of the vasculature and blood flow • Diseases of the vascular system • Fundamental cardiac electrophysiology • Recognition and interpretation of normal ECG waveforms Control of the circulation • Cardiac embryology and foetal heart development • Atherosclerosis and its relationship with cardiovascular disease • Heart failure and its effect on the cardiovascular and other body systems • Introduction to Respiratory and Sleep Science • Anatomy and physiology of the respiratory system • Anatomy and physiology of central and autonomic nervous systems • Control of respiration during sleep • Control of sleep wake cycle • Pathophysiology of lung diseases • Pharmacology and therapeutics

Special Features

This module will be supported by the very strong science base within the University of Southampton. We have very successful programmes in life sciences, medicine, engineering and science (including the Institute of Sound & Vibration Research) all of which are well resourced in both staff and equipment. It is our intention to maximise opportunities for our students to work within this robust academic environment by sharing learning opportunities and being exposed to experts in the field. Students will have access to state of the art laboratories both on Highfield campus and at University Hospital Southampton which are fully equipped with learning resources and specialist equipment each speciality. The human morphology laboratory, for instance, will provide a strong learning environment for our students as they are introduced to anatomy and physiology. In order to support this programme, the Faculty has invested in four new ‘Lab-Tutor’ simulated learning software packages with the associated hardware. These will supplement the existing simulated learning equipment (SimMan) which have been used very successfully on our existing programmes.

Learning and Teaching

Teaching and learning methods

Students will learn by exploring material in seminars and laboratory practical’s in conjunction with directed learning. Students will be encouraged to take responsibility for the development of their own learning by utilising a variety of means such as multimedia resources, and the library, and by self-directed development of the study skills necessary to access these resources.

External visits8
Preparation for scheduled sessions20
Practical classes and workshops10
Total study time186

Resources & Reading list

Lee-Chiong, T. (2006). Sleep: a comprehensive handbook. 

Guyton, A. & Hall, J. (2009). Textbook of Medical Physiology. 

Opie,l. (2004). Heart Physiology: From Cell to Circulation. 

McNicholas, W & Phillipson, E. (2008). Breathing Disorders in Sleep. 

MacIntyre, N & Branson, R. (2009). Mechanical Ventilation. 

Mitler, M. & Poceta, J. (1998). Sleep disorders: diagnosis and treatment. 

Morris, F. (2008). The ABC of Clinical Electrocardiography. 

Tortora, G. (2009). Principles of Anatomy and Physiology. 

Kumar, P. & Clark, M. (2009). Clinical Medicine. 

Phillips, B. (2004). Obstructive Sleep Apnea. 

Bourke, S. (2003). Lecture notes on respiratory medicine. 

West, J. (2008). Pulmonary Pathophysiology. 

Simonds, A. (2007). Non-invasive respiratory support: a practical handbook. 

Kushida, C. (2008). Handbook of Sleep Disorders. 

Chokroverty, S. & Thomas, R. (2005). Atlas of Sleep Medicine. 

Klabunde, R. (2005). Cardiovascular Physiology Concepts. 

Cotes, J., Chinn, D. & Miller, R. (2006). Lung function: physiology, measurement and application in medicine. 

Ward, J., Ward, J. & Weiner C. (2006). The Respiratory System at a Glance. 

Cooper, B. (2005). Practical handbook of respiratory function testing: Part One and Part Two. 

Marieb, E. (2004). Human Anatomy & Physiology. 

Aaronson, P., Ward J & Connolly, M. (2012). The Cardiovascular System at a Glance. 

Sunthareswaran, R. (2004). Cardiovascular System. 

Butkov, N., Lee-Chiong, T. (2007). Fundamentals of sleep technology.. 

This module is fully supported by an online learning system (Blackboard Academic Suite) which enables students to access course information, course resources, lecture notes and power-point presentations. It also enables them to share information through d. 



MethodPercentage contribution
Written exam  (1.5 hours) 100%

Repeat Information

Repeat type: External

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