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The University of Southampton

HPRS1026 Scientific Basis of Healthcare Science (Part 1)

Module Overview

This module will provide a basic yet broad foundation in the sciences that underpin the practice of Health Care Sciences. It will enable students to gain an integrated understanding of anatomy, physiology and pathphysiology from the cellular level to the level of whole body systems. It will provide a foundation in key scientific principles applicable to the human condition such as the introductory pharmacology.

Aims and Objectives

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Explain the chemical, cellular and tissue level of organisation of the body and the structure and function of the cell
  • Understand basic mathematical concepts.
  • Explain the basic principles of pharmacology, pharmacokinetics and therapeutics including drug names and classifications, definitions of terms and basic mechanisms
  • Become recipients of research evidence in healthcare science by considering the range of research activity in healthcare science / cardiac physiology / respiratory & sleep physiology by accessing professional journals and associated literature.
  • Describe the anatomy, physiology and pathology of the body across the Brain, Integumentary, Skeletal, Nervous, Cardiovascular (including blood, blood vessels and lymphatic system), Respiratory, Endocrine, Renal, Gastrointestinal (including nutrition), Urinary and Reproductive Systems.
  • Explain the cellular, tissue and systems responses to disease including cell death, inflammation, neoplasia, hypertrophy, hyperplasia, tissue responses to injury and repair.
  • Explain the basic principles of histology.
  • Describe the pathophysiology of disease development in common diseases across the body systems.
  • Examine patients' responses to illness and treatment and consider the impact of psychological and social factors, including culture, on health and health-related behaviour.
  • Recognise the difference between pharmacology, clinical pharmacology, therapeutics and prescribing and medicine management.
  • Explain the basic principles of microbiology including natural defences, infection control, bacteria, recognition of extracellular pathogens, virus types and structures, viral infection and replication.
  • Explain how reference ranges are generated and their limitations.
Subject Specific Intellectual and Research Skills

Having successfully completed this module you will be able to:

  • Respect and understand individuals’ beliefs and ways of coping with illness.
  • Demonstrate knowledge of the influence of culture and beliefs on health.
  • Use a range of study skills including time management, organisational skills, using the library, search engines, self-directed learning, critical analysis and avoiding plagiarism.


The Health Science students will be directed to attend compulsory lectures which are identified as essential to underpin their future practice. In addition to the lead lectures, a series of ‘Health Science specific’ practical classes and seminars will reinforce and build on core lecture content. A broad introduction to key knowledge and principles across body systems will be complimented with an introduction to the basic principles of physics, psychosocial science and biological concepts that underpin healthcare science. Indicative Content Basic principles of • The cell • Microbiology/infection Control • Immunology • Pharmacology, Therapeutics, Pharmacokinetics Introduction to Anatomy, Physiology and Pathology across body systems Cellular, tissue and systems responses to disease Pathophysiology of disease development in common diseases across the body systems Basic principles of mathematics and statistics

Learning and Teaching

Teaching and learning methods

Learning opportunities will include both profession specific learning and learning alongside students from other Faculty of Health programmes. The teaching and learning methods will include lectures, seminars, practical classes and self-directed study. Learning will be augmented by electronic learning resources, core texts and directed study activities. Learning of anatomy will be supported by practical sessions in the Anatomical Sciences Laboratory and the use of online anatomy resources. Students will be encouraged to take responsibility for the development of their own learning by utilising a variety of means such as multi-media or online academic resources, the library, and the Anatomical Sciences Laboratory and by self-directed development of the study skills necessary to access these resources.

Preparation for scheduled sessions27
Wider reading or practice100
Total study time187

Resources & Reading list

Author: Rang & Dale, Edition: Seventh (2011). Rang & Dale’s Pharmacology. 

Elaine Marieb & Katja Hoehn (2004). Human Anatomy & Physiology. 

Author: Gabriel Virella, Editor: Gabriel Virella (2011). Medical immunology. 

Acland’s video Atlas of Human Anatomy.

McCance and Huether (2010). Pathophysiology: the biologic basis for disease in adults and children. 

Author: Bruce Alberts, Editor: Bruce Alberts (2013). Essential cell biology: an introduction to the molecular biology of the cell. 

Kumar, Abbas and Aster (2013). Robbins basic pathology. 



Online Extended Matched Questions (EMQ) and short answer questions


MethodPercentage contribution
Timed and unseen Extended Matched Questions (EMQ) and short answer examination  (90 minutes) 100%


MethodPercentage contribution
Timed and unseen Extended Matched Questions (EMQ) and short answer examination 100%

Repeat Information

Repeat type: External

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