Skip to main navigationSkip to main content
The University of Southampton

HPRS3019 Advanced Respiratory and Sleep Physiology

Module Overview

The overall aim of this module is to ensure that the student begins to gain wider knowledge of investigations undertaken in Respiratory and sleep. This module will build on modules completed earlier in the course to equip the student with the knowledge they need to undertake and interpret a high quality measurement.

Aims and Objectives

Module Aims

To ensure that the student develops knowledge and understanding of a wider range of investigations utilised within Respiratory and Sleep Sciences and their application in relevant care pathways

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Discuss the range of respiratory and sleep physiology investigations commonly undertaken.
  • Explain the underpinning basic and clinical science and analyse results from the following: • Blood Gas Analysis • Respiratory Sleep Studies • Challenge Testing
  • Explain human development from birth to adulthood with respect to the Respiratory system.
  • Describe the differences between children and adults with respect to respiratory physiology investigations.
  • Explain the methods available for assessing respiratory function in children ≥ 8 years.
  • Demonstrate an understanding and experience of the value of clinical audit in optimising services.
  • Justify the importance of patient-centred care.
  • Describe the range of needs of people with disabilities within this care pathway and explain how to accommodate them to undertake respiratory and sleep studies.
  • Engage with research activity by evaluating research outcomes in cardiac physiology / respiratory & sleep physiology and judiciously applying them to professional practice.
Subject Specific Intellectual and Research Skills

Having successfully completed this module you will be able to:

  • Respect and uphold the rights, dignity and privacy of patients.
  • Establish patient-centred rapport.
  • Appreciate the empathy and sensitivity needed when dealing with the patient experience of long term conditions and terminal illness.
  • Actively seek accurate and validated information from all available sources with respect to respiratory investigations.
  • Select and apply appropriate analysis or assessment techniques and tools.
  • Critically discuss the problems associated with the care of patients undergoing respiratory investigations or treatments.


Patient Centred Care • Communication Skills • Consent • Confidentiality • Disability including learning disabilities • Care Pathways for patients with respiratory disease • Problems associated with care Blood gas measurement • Physiological processes that contribute to the maintenance of normal • blood gases • Gas exchange • Gas transport • Acid base balance and blood gases • Safety procedures • Characteristics and function of analysers • Sampling procedures • Normal values Sleep Studies • Sleep physiology • Sleep pathophysiology • Lung function and sleep • Obstructive sleep apnoea • Overnight oximetry • Airflow and respiratory effort in sleep • Epworth sleepiness scale • Indications for polysomnography • Indications for CPAP therapy • Driver and Vehicle Licensing Agency (DVLA) regulations Challenge Testing Methods for assessing airway reactivity Indications and contra-indications for testing Safety precautions and safe handling of reagents Representation of results Skin allergy testing

Special Features

This module will be supported by the very strong science base within the University of Southampton. We have very successful programmes in life sciences, medicine, engineering and science (including the Institute of Sound & Vibration Research) all of which are well resourced in both staff and equipment. It is our intention to maximise opportunities for our students to work within this robust academic environment by sharing learning opportunities and being exposed to experts in the field. Students will have access to state of the art laboratories both on Highfield campus and at the Southampton General Hospital which are fully equipped with learning resources. The human morphology laboratory, for instance, will provide a strong learning environment for our students as they are introduced to anatomy and physiology. In order to support this programme the Faculty is investing in four new ‘Lab-Tutor’ simulated learning software packages with the associated hardware. These will supplement the existing simulated learning equipment (SimMan) which have been used very successfully on our existing programmes.

Learning and Teaching

Teaching and learning methods

Students will learn by exploring material in seminars and laboratory practical’s, in conjunction with directed learning. Students will be encouraged to take responsibility for the development of their own learning by utilising a variety of means such as multimedia resources, and the library, and by self-directed development of the study skills necessary to access these resources.

Wider reading or practice200
Completion of assessment task45
Preparation for scheduled sessions20
Total study time375

Resources & Reading list

John Burnard West (2008). Pulmonary pathophysiology: the essentials. 

Terry Des Jardins, George G. Burton (2010). Clinical Manifestations and Assessment of Respiratory Disease. 

Authors: W. T. McNicholas, Eliot A. Phillipson, Editors: W. T. McNicholas, Eliot A. Phillipson (2002). Breathing disorders in sleep. 

Author: Clete A. Kushida, Editor: Clete A. Kushida (2008). Handbook of Sleep Disorders. 

Authors: Neil R. MacIntyre, Richard D. Branson, Editors: Neil R. MacIntyre, Richard D. Branson (2009). Mechanical ventilation. 





MethodPercentage contribution
Written essay  (2000 words) 50%
Written exam  (2 hours) 50%


MethodPercentage contribution
Written essay 50%
Written exam 50%

Repeat Information

Repeat type: External

Share this module Share this on Facebook Share this on Twitter Share this on Weibo

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.