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The University of Southampton
Courses

BIOL6037 The Pathophysiology of the Lung

Module Overview

The unit comprises lectures on the risk factors, pathophysiology and therapy for three very common but distinct lung diseases, asthma, COPD and cystic fibrosis. We will examine current therapies and the development of new approaches based on our understanding of the underlying disease mechanisms. In addition to an in depth exploration of pulmonary disease pathology we will examine the role of early life factors such as infections and genetics influences the outcomes in chronic lung disease.

Aims and Objectives

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Explain the role of different cell types in allergic disease.
  • Discuss the implications of a sample of current research in this field for our understanding of lung disease
  • Identify the pathways responsible for the synthesis of immunoglobulin E
  • Identify the major pharmacological targets available to treat allergy and asthma and emerging therapeutic targets.
  • Discuss our current understanding of the influence of early life factors on the development of allergic disease.
  • Describe the main characteristics of chronic obstructive pulmonary disease (COPD) and current hypotheses pertaining to its pathology.
  • Identify the problems associated with treating COPD and some of the potential therapeutic strategies.
  • Discuss the impact of viral and bacterial infections on chronic lung diseases
  • Describe the clinical symptoms and cellular pathology underlying cystic fibrosis.
  • Discuss the concepts and technical approaches to cystic fibrosis therapy

Syllabus

The unit comprises lectures on the risk factors, pathophysiology and therapy for three very common but distinct lung diseases, asthma, COPD and cystic fibrosis. We will examine current therapies and the development of new approaches based on our understanding of the underlying disease mechanisms. In addition to an in depth exploration of pulmonary disease pathology we will examine the role of early life factors such as infections and genetics influences the outcomes in chronic lung disease.

Learning and Teaching

Teaching and learning methods

Lectures, research paper seminars and independent study

TypeHours
Independent Study122
Seminar4
Lecture24
Total study time150

Assessment

Summative

MethodPercentage contribution
Literature review with presentation  (1500 words) 35%
Written exam  (2 hours) 65%

Referral

MethodPercentage contribution
Literature review with presentation 35%
Written exam  (2 hours) 65%

Repeat Information

Repeat type: Internal & External

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