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The University of Southampton
Courses

BIOL6040 Development Origins of Health and Disease

Module Overview

This module seeks to understand the broad physiological principles that progress from the early embryo through to the later stages of fetal development, birth and early postnatal life using the Developmental Origins of Health and Disease (DOHaD) hypothesis as a conceptual framework.

Aims and Objectives

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • To understand major scientific principles linking maternal, placental, embryonic, fetal and neonatal physiology
  • To critically evaluate primary literature relating to selected areas of maternal-placental-fetal-neonatal physiology.
  • To consider the wider implications (in terms of adult health, ethics etc.) of feto-placental physiology
  • To develop transferable skills in critical analysis of papers, their methodologies / techniques and summarising of scientific ideas through writing (including written paper methodology critique), discussion and oral presentation of a selected scientific research paper.

Syllabus

The BIOL 6040 course focuses on exciting new developments in the fields of embryonic, placental and fetal physiology. The course takes a developmental approach from ‘Early development’ to ‘Placentation and maternal adaptation’ to ‘Fetal Development and life after birth’. Clearly each of these areas alone could comprise an undergraduate course, and it is not the objective of this course to fit 3 semesters work into one. Your goal has to be to get to grips with broad physiological principles that progress from the early embryo through to the later stages of fetal development, birth and early postnatal life and to use the Developmental Origins of Health and Disease (DOHaD) hypothesis* as a conceptual framework or theme upon which to base your learning. *The DOHaD hypothesis suggests that the prevalence of adult diseases such as coronary heart disease, stroke, hypertension, diabetes and the metabolic syndrome has a developmental origin (i.e. embryonic and fetal stages of development).

Learning and Teaching

Teaching and learning methods

Lectures Independent study Round table discussions Critical evaluation of scientific papers (through paper discussion sessions and independent reading, oral presentation of a selected scientific paper and written critique of techniques and methodology of a selected scientific research paper) Visits to IVF clinic and Southampton Women’s Survey

TypeHours
Independent Study125.5
Tutorial0.5
Demonstration1
Supervised time in studio/workshop7
Lecture16
Total study time150

Assessment

Assessment Strategy

Assessment & Assessment Weighting Examination 2 hour paper, 2 essays In module assessment 15% essay, 5% round table write ups, 10% presentation of scientific paper, 10% written critique of technical / methodology aspects of scientific paper Re-assessment Method Assessment & Assessment Weighting Examination 2 hour paper, 2 essays In module assessment : marks carried forward (In 2018/19 this module was renamed and was formerly known as 'Maternal, Fetal and Neonatal Physiology')

Summative

MethodPercentage contribution
Coursework 40%
Written exam  (2 hours) 60%

Referral

MethodPercentage contribution
Coursework 40%
Written exam  (2 hours) 60%

Repeat Information

Repeat type: Internal & External

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