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The University of Southampton

CHEM6143 Delivering Analytics: From Experiment to Exploitation

Module Overview

Analytical chemistry covers a broad and diverse range of employment opportunities within academe and the industrial arena: • throughout pharmaceutical chemistry from structural elucidation at the very beginning of the drug discovery process to designing robust QC test regimes in the discovery phase • agrochemicals research • the petrochemical industry • environmental testing The successful operation of an analytical facility to deliver these critical data, requires both an understanding of the technical elements of an individual experiment but also an appreciation of numerous other aspects that must be adhered to in order to claim full scientific integrity and rigour. Good laboratory practice (GLP) is a concept applicable not only to the way an individual conducts an experiment but also to how a facility is operated. There are industry standards that are expected and imposed in virtually every workplace in the chemical industry and these are used not only to ensure safe, productive and accurate working but are also considered as part of the standard working model that fundamentally protects the intellectual property that the business generates. This module will introduce GLP, the appropriate use of electronic recording of experiments, good data management practice, IP protection and exploitation, facility management practice and embed team management skills in the context of delivering robust and reliable analytical solutions. The module will use as inspiration examples from the core Characterisation and Analytics Facilities at Southampton and in particular the UK National Crystallography Service.

Aims and Objectives

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Appreciate the range and diversity of opportunity in analytical chemistry
  • Understand the business and operating models behind commercial and academic analytical facilities
  • Understand the principles behind thorough data and facility management
  • Apply GLP principles to the protection and exploitation of IP in both academic and commercial environments


1. Employability (invited speakers from industry) 2. Understanding analytical chemistry in industry: Discovery vs. Development • Multiple technique based structural elucidation strategies • Design of robust protocols for routine QC 3. Running a facility • GLP principles and regulations • Facility, personnel and performance • Reporting and record keeping • Electronic Laboratory Notebooks • Laboratory Information Management Systems • Long term curation and the scientific record • Access and user management 4. Financing a facility • Funding instrument purchases • Instrument support and maintenance • Costing and charging for access • Financing of start-up companies 5. Team skills and Management 6. Making the most of your results: communicating results on different levels • Introduction to patent law • Scientific publication practices: reports, posters, presentations and peer-reviewed journals

Learning and Teaching

Teaching and learning methods

Teaching Methods • Lectures (including visiting lecturers from commercial environments) • Personal record taking, evaluation and reflection in practical situations • Small-group problem solving • Workshops involving interaction with the instrumentation in small groups • Directed reading and online tutorials • Bb online support Learning Methods Independent study, independent reflection, student motivated peer-group study, student driven tutor support, individual practical (instrument-based) experience

Preparation for scheduled sessions4
Follow-up work12
Wider reading or practice12
Completion of assessment task90
Total study time150



MethodPercentage contribution
Business case 40%
Coursework 40%
Viva 20%


MethodPercentage contribution
Coursework 80%
Viva 20%
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