Human Structure & Function 1 will enable you to understand key physiological, anatomical & biochemical concepts and principles that you can apply in problem based scenarios.
This will prepare you to successfully undertake the early years of the BM programme. You will specifically study; the structure and function of biological macromolecules and the principles of metabolism; principles of homeostasis & homeostatic imbalance, particularly as applied to the cardiovascular system; the structure & function of cells & tissues; basic anatomy; nutrition & the digestive system; principles of enzymology and energetics; principles of medical microbiology and immunology.
Aims and Objectives
Having successfully completed this module you will be able to:
- Assess the role of cell membranes in membrane transport, membrane potentials and cellular communication
- Indicate development of independent working skills, team working and problem solving skills
- Explain the key features of a balanced diet
- Explain the structural organisation of the human body
- Demonstrate a sound understanding of the principles of isomerism, energetics, redox reactions, metabolism and metabolic pathways including cellular respiration
- Describe the principles of immunology and the features of immuno-protection, immune reaction and auto-immune disease
- Identify basic anatomical structures and terminology
- Demonstrate skills in reading and research in specified topics
- Compare the features of specialised body tissues
- Explain the process of digestion and absorption of macromolecules
- Demonstrate an understanding of cell structure and function
- Assess the features of disease-causing micro-organisms and the consequences of infection
- Describe the structure and characteristics of biological macromolecules
- Analyse, present and manipulate data
- Communicate effectively using oral, writing and computing skills
- Demonstrate by reference to specific examples an understanding of the characteristics of homeostatic mechanisms and homeostatic imbalance
- Demonstrate a sound understanding and the application in the human body of ionisation, kinetics and enzymology
In order to meet the learning outcomes, the syllabus will contain teaching in the following areas:
- Structural organisation of the body
Key features of cells, tissues and systems in the body and the principle of complementarity of structure and function
Concepts and mechanisms involved in regulation of the internal environment with examples of homeostatic imbalance.
- Cell biology
Structure and function of cell organelles and cytoskeletal elements. Consequences of organelle dysfunction and cellular response to stress.
Structure and function of membranes, associated membrane specialisations and cell junctions. Chemical and electrical gradients across the cell membrane and the basis of the resting membrane potential and membrane transport.
- Medical microbiology
Microorganisms of relevance to medicine. Structure and characteristics of bacteria and viruses. Aspects of selected bacterial and viral diseases including the use of antibiotics and antivirals.
- The human body’s defences
Specific and non-specific defences. Types of immunity and key features of the immune system. Characteristics and examples of autoimmune diseases and hypersensitivity reactions.
Basic anatomical terminology of regions of the body, planes of section and movement. Location of gross anatomical structures.
- Structure and characteristics of biological macromolecules
Structure, bonding and organisation of proteins, lipids, carbohydrates and nucleic acids. The role of macromolecules in health and disease.
- Basic nutrition and diet
The role of macromolecules and micromolecules in a balanced diet and in dietary restrictions and disorders.
- Digestion and absorption of key macromolecules
Chemical and mechanical digestion and absorption of proteins, lipids and carbohydrates. Conditions of maldigestion and malabsorption.
- Principles of isomerism, ionisation, kinetics and enzymology
Different types of isomers. Potential and kinetic energy. Effects of ionisation on the structure and function of proteins. Enzymology and factors affecting the rate of reactions.
- Principles of energetics, metabolism and metabolic pathways
Key aspects of metabolism. Overview of key metabolic pathways, their integration and control.
- Redox reactions
Principles of redox reactions. Structure and function of the electron transport chain. Electron transport chain uncouplers and inhibitors
Learning and Teaching
Teaching and learning methods
The module will be taught through a range of face to face and online learning and teaching strategies which will include:
- Tutor led tutorials
- Practical sessions
- Guided self-study
- Problem solving scenarios
- Group work
|Completion of assessment task||60|
|Wider reading or practice||24|
|Preparation for scheduled sessions||50|
|Practical classes and workshops||10|
|Total study time||298|
Resources & Reading list
Marieb EN, Hoehn K. (2013). Human Anatomy & Physiology. London: Pearson.
Baynes J, Dominiczak MH. (2014). Medical Biochemistry. Mosby Elsevier.
Students are not normally permitted to repeat the year.
This is how we’ll give you feedback as you are learning. It is not a formal test or exam.Essay
This is how we’ll formally assess what you have learned in this module.
This is how we’ll assess you if you don’t meet the criteria to pass this module.
Repeat type: External